RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
SOCS1
RNA ID
RNA Type
mRNA
Alteration Pattern
socs1 methylation
Species
homo sapiens
Detection Methods
RT-PCR; immunohistostaining etc.
Target
SOCS1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis
Year
2004
Function
Genetic and pharmacologic disruptions of mecp2 or ezh2 reduced the fibrogenic characteristics of myofibroblasts and attenuated fibrogenesis.